On Day 2 of the regular season game of the 2025-26 NBA season, the matchup between the New York Knicks and the Cleveland Cavaliers will go live on October 22, 2025, with kickoff at 7:00 pm ET from the Madison Square Garden in New York. The Knicks will play host to the Cavs for their first face-off this season, and both teams are looking to start their campaign strong. The Knicks have home ground advantage over their opposition, but the Cavs who finished top of the table during the regular season last time will also play to their advantage.
New York Knicks injury report against Cleveland Cavaliers (October 22, 2025)
The New York Knicks ended as the 3rd seed in the Eastern Conference at the end of the regular season last time, but have a pretty depleted roster with a lot of players out injured, including Mitchell Robinson and Karl-Anthony Towns. With half the roster gone, let’s see who are expected to make the starting line-up for their opening match and who will miss out. New York Knicks Injuries:Josh Hart (back) – OutMitchell Robinson (ankle) – OutKarl-Anthony Towns (quad) – QuestionableOG Anunoby (ankle) – ProbablePredicted starting line-up:Jalen BrunsonMikal BridgesPacome DadietGuerschon YabuseleAriel Hukporti
Cleveland Cavaliers injury report against New York Knicks (October 21, 2025)
The Cleveland Cavaliers will be without two of their main players – Darius Garland and De’Andre Hunter, who are both out with injury against the New York Knicks. Garland will be out for the foreseeable future with a long-term recovery, but Hunter is expected to make his return as soon as their next match-up if health permits. Let’s see who will be available and who will miss out on their first game of the season. Cleveland Cavaliers Injuries:Max Strus (foot) – OutDarius Garland (toe) – OutDe’Andre Hunter (knee) – QuestionablePredicted starting line-up:Donovan MitchellLonzo BallDean WadeEvan MobleyJarrett Allen
New York Knicks vs. Cleveland Cavaliers game information:
Time: Tuesday, October 22, 2025 at 7:00 p.m. ETVenue: Madison Square Garden, New YorkStreaming Info: NBC/PeacockAlso Read: New York Knicks vs. Cleveland Cavaliers (10-22-2025) game preview: When and where to watch, expected lineup, prediction, and more
